KESKUSTELU

Sekoitat korrelaation ja kausaliteetin.

Cum hoc ergo propter hoc.


No älä sitten ota aurinkoa jos menee noin vaikeaksi. Deetä saa purkistakin - ei tämä ole mikään auringonhypetysketju itsessään.


Edelleen, ihmiset EIVÄT yleensä lue lääkkeittensä tuoteselosteita. Se ei ole minun vikani.


Mutta silloin ei muodostu D-vitamiinia, turha kuvitellakaan.


Alpit ovat vieä suhteellisen pohjoisessa, kuten voit kartalta helposti itsekin todeta. Aurinkolomat kestävät 1-2 viikkoa, usein ei mene kuukauttakaan kun kalsidiolitasot ovat jälleen pohjamudissa. Hurjat heilahtelut kalsidiolitasoissa voivat olla vaaraksi - siksi olisi ilmeisesti fiksua pitää tasainen saanti yllä. Tropiikissa näin rajuja heilahteluita EI ole ja keskimääräiset tasot ovat jatkuvasti ainakin kolminkertaiset.

Voin antaa niin paljon rautalankaa kuin ikinä haluat:




Syyt siihen miksi ihosyövät ovat yleistyneet, ovat moninaiset.
Mikäli et vieläkään ole valmis selaamaan ketjua taaksepäin, niin lue/katso edes nämä:

http://www.toyourhealth.com/mpacms/tyh/ ... hp?id=1195

http://www.freetheanimal.com/root/2008/ ... creen.html

http://www.youtube.com/watch?v=eeXtGHSt-5o


Aurinkorasvat mm. päästävät UVA-säteilyä läpi MUTTA blokkaavat käytännössä kaiken D-vitamiinia tuottavan JA melaniinin muodostumista lisäävän UVB-säteilyn. Toiseksi aurinkorasvat ehkäisevät ihon punoitusta, mikä on luonnon oma keino viestiä ihmiselle että on korkea aika mennä varjoon. Seurauksena ihon palamista ja ihosyöpäriskin kasvua rasvojen_käytöstä_huolimatta. Niin ja eipä unohdeta että monet aurinkorasvojen (teho)aineet imeytyvät ihon läpi ja kulkeutuvat sisäelimiin - toisin sanoen aurinkorasvat ovat suositeltavia mikäli olet valmis myös syömään niitä.

Niinpä. Kuinka paljon on suojarasvojen käyttö lisääntynytkään viime vuosina? Samassa suhteessa kuin ihosyöpä?


Siksi niitä ei lapsille suositellakaan. Ne ovat myrkkyä. Tuskin ne aikuisillekaan kovin terveellisiä silloin ovat?
Apteekista saa "terveellisempiä" vaihtoehtoja, mutta ei nekään myrkyttömiä ole.

Itse tilannu Melatoniinit DHEA Storesta, valikoimalla ei pääse hifistelemään ja hintakin snadisti kalliimpi kuin iHerbillä. Tulevat kuitenkin tavallisessa ruskeassa pehmustetussa kirjekuoressa muovipussissa tekaistulla lähettäjänimellä. Ei siis selittelyistä tai sanktioista pelkoa. Vähän epäilytti aluks semmoset "irto"pillerit, muttei ne purkitkaan takaa, ettei joka kymmenes oo vaikka syaniidii. Ja hyvin ovat toimineet muillakin kuin mulla.

Feno katkasussa?

Muistutan vielä ystävällisesti tuhannennen kerran, että aurinkorasvat ->

JOKA
TAPAUKSESSA
LISÄÄVÄT
SYÖPIÄ
ESTÄMÄLLÄ
IHON
KOLEKALSIFEROLISYNTEESIÄ



Katsokaa nyt vielä kerran: pelkästään paksusuolensyövän tapaukset laskettuna aurinkoisemmassa eteläisessä USA:ssa ovat kasvaneeseen ihosyöpäriskiin verrattuna KYMMENKERTAISET!

Ottakaa se laskin esiin jo lopultakin!!!

No one is suggesting that people fry on a beach. But many scientists believe that "safe sun" — 15 minutes or so a few times a week without sunscreen — is not only possible but helpful to health.

One is [b]Dr. Edward Giovannucci, a Harvard University professor of medicine and nutrition who laid out his case in a keynote lecture at a recent American Association for Cancer Research meeting in Anaheim, Calif.

His research suggests that vitamin D might help prevent 30 deaths for each one caused by skin cancer.

"I would challenge anyone to find an area or nutrient or any factor that has such consistent anti-cancer benefits as vitamin D," Giovannucci told the cancer scientists. "The data are really quite remarkable."[/b]

Suomen D-vitamiiniekspertti Heli Viljakainen

"Tutkijat arvioivat, että Yhdysvalloissa D-vitamiinin puutos on syynä tuhansiin syöpäkuolemiin joka vuosi."

http://www.kaleva.fi/plus/index.cfm?j=752216

Ai niin ja aina uusien aurinkorasvojen markkoille tulon myötä melanoomat ovat kasvaneet. Mielenkiintoinen sattuma!

The sunscreen manufacturers are doing just fine.

http://www.freetheanimal.com/.a/6a00d83 ... b2e970b-pi


Really, really fine. The more money they make, the more melanoma, and the more calls go out to use more sunscreen. Excellent business plan.

http://www.freetheanimal.com/.a/6a00d83 ... e98970c-pi


Cannell:

Dr. Cannell: Should I use sunscreens or cosmetics that contain sunscreens?

Hundreds of people have asked me this question. It's important to remember that many cosmetics contain sunscreens. My short answer is: "If you are comfortable drinking sunscreens, then you should feel comfortable putting them on your skin." At least three studies have found that the chemicals commonly used in sunscreens are absorbed through the skin and end up circulating in your blood stream. As they circulate in your blood, they go to your internal organs—where they do whatever those chemicals may do there. Then they are excreted in your urine. If you drink them the same thing would happen. Sunblocks that have old style zinc or titanium oxide as their only active ingredients are not absorbed by the skin. Zinc oxide used to be a gooey paste, now it is emulsified, and may, or may not, be absorbed systemically. It blocks light, just like clothes. I remember a beach in France where a beautiful young woman had carefully applied the old gooey red zinc oxide to her body in the shape of a tiny red bikini. She couldn't sit down because the sand would stick to her. She was naked but you had to look twice (which I did) to see just how naked she was. 1 2 3

Furthermore, sunscreens facilitate the skin's absorption of pesticides. So, if you want pesticides to be readily absorbed through your skin, circulate in your blood, go to your internal organs, and be excreted in your urine, wear sunscreens. Or, you could take a swig of your Coppertone and chase it with a shot of Deepwoods Off. 1 2 3 4

Finally, if you think your sunscreen is preventing your skin from turning red just by blocking solar radiation, think again. [b]Sunscreens inhibit an enzyme in your skin that makes nitric acid and one of the functions of nitric acid is to inflame your skin. The inflammation then signals your immune system to start protecting your skin and tells you to get out of the sun. Sunscreens block nitric acid formation, the skin doesn't redden, the immune system isn't notified, you stay longer in the sun, your skin is damaged, and you increase your risk of skin cancer and premature aging.[/b]1

I call this combination of events—drinking sunscreen and insecticides while blocking your immune system's ability to protect your skin—the "Gilchrest Phenomenon," named after the Chairwoman of Dermatology at Boston University who funds her department with grants from the sunscreen/cosmetic industry.

http://www.vitamindcouncil.org/newslett ... -aug.shtml

Eli kielirajoitteisille tiivistys:

1: Sinkki- tai titaanioksidia sisältävät perinteiset tahnamuotoiset rasvat eivät imeytyneet, nykyiset saattavat imeytyä. Muista rasvoista aineita päätyy verenkiertoon ainakin kolmen tutkimuksen mukaan ja siten niiden käyttö on verrannollista aurinkorasvojen laittamiseen leivän päälle tai salaattiin. Be my guest...

2: Aurinkorasvat estävät iholla typpihapposynteesiä salpaamalla tämä aikaan saavaa entsyymiä, mikä johtaa siihen ettei iho punerru ennen palamista. Tämä suojamekanismi siis ehkäisee ihon palamista ennakkovaroituksella, mistä tulee myös nimitys erytmaattinen annos - tämän jälkeen D-vitamiinia ei enää synny iholla lisää.

3: Ihon palaminen vaivihkaa myös tuhoaa jo synteesivaiheessa olevaa D-vitamiinia - jos sitä on ehtinyt muodostua ennen aurinkorasvan lisäämistä. Iho ikääntyy myös nopeammin ja ihosyöpäriski kasvaa.

4: Aurinkorasvat lisäävät tuholaismyrkkyjen imeytymistä iholta verenkiertoon. Erittäin hyvä käyttää aurinkorasvaa toisin sanoen mm. työskennellessä pellolla jonne on juuri ruiskutettu pöpömyrkkyjä. Vastaa siis jälleen niiden syömistä ja tuholaismyrkkyjä voi takuulla pitää myrkkyinä myös ihmisille.

Lasten diabetestapaukset nousussa!

"""Nuoruustyypin diabetekseen sairastuvien alle viisivuotiaiden määrä saattaa kaksinkertaistua Euroopassa ensi vuosikymmenen loppuun mennessä, varoitetaan Lancet-lehdessä julkaistussa tutkimuksessa.

Seitsemäntoista Euroopan maata kattavassa selvityksessä nuoruustyypin diabeteksen havaittiin yleistyvän vuosittain noin 4 %. Suurinta lisäys oli alle viisivuotiaiden ryhmässä.

Vuonna 2005 noin 15 000 alle 14-vuotiasta eurooppalaista sairastui nuoruustyypin diabetekseen. Vuonna 2020 uusia tapauksia todetaan jo yli 24 000 vuodessa, tutkijat arvioivat.

Kun mukaan lasketaan jo olemassa olevat tapaukset, vuonna 2020 arviolta 160 000 eurooppalaislasta sairastaa nuoruustyypin diabetesta. Vuonna 2005 luku oli 94 000.

Muutos on niin nopea, etteivät yksistään perinnölliset seikat voi sitä selittää. Mahdollisesti kehitys johtuu muutoksista elintavoissa ja ympäristössä, lasten aiempaa nopeammasta pituuden ja painon kehityksestä tai keisarileikkausten yleistymisestä, tutkijat uskovat.

Suomessa nuoruustyypin diabeteksen ilmaantuvuus on viisinkertaistunut 1950-luvun jälkeen ja kehityksen uskotaan jatkuvan samansuuntaisena. Uusia tapauksia todetaan meillä jo nyt enemmän kuin missään muussa maassa.

Nuoruustyypin eli tyypin 1 diabeteksessa haima ei pysty tuottamaan riittävästi insuliinia ja tämän takia veren sokeripitoisuus voi nousta vaarallisen suureksi. Noin 40 000 suomalaista sairastaa tyypin 1 diabetesta. Taudin aiheuttajaa ei tiedetä."""

http://www.poliklinikka.fi/?page=7874754&id=7714900

Tutkiikohan kukaan voiko krooninen D-vitamiinin vaje koko euroopan alueella aiheuttaa I-tyypin diabetesta?

Vaikuttaa jo maaniselta.. Huomatkaa Neonomiden paikkakunta: Riversmouth. Missä ikinä lienee. Luultavasti jenkkilässä, koska hypetyskin sen mukaista. Suurin osa kaverin linkeistä ja lähteistäkin peräisin sieltä. Siellä, kun tuo nanoteknologia jyllää ja niitä hiukkasia saattaa siellä rasvapurkeissakin olla. Suomessa ostan aurinkorasvani apteekista. Omasta mielestäni muita hyviä vaihtoehtoja ei ole.

Sitä rautalankaa otan vastaan kyllä, kunhan se on aitoa rautaa!

Vaikka ei pitäisi jonkun tavasta kirjoittaa tai "hypetyksestä" tai edes kirjoituksen sisällöstä, niin tutkimukset on otettava tutkimuksina, niitä voi epäillä, mutta se ei ole tutkimuksen esiintuojan vika tai syy, jos siitä on huomauttamista. Ja ketjun kommentointi on arveluttavaa, jos ei ole lukenut sitä.

PS. Suomen paikkakuntien englannistaminen on ns. huumoria.

Jepjep, jos kolmekymmentäkertainen syöpäriski kiinnostaa, niin vitsaillaan vaan D-vitamiinista vaikka tuomiopäivään asti.

Kuten filosofi Arthur Schopenhauer sanoi:

“First, the truth is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.”

Syöpätutkija William Grantin mukaan olemme D-vitamiinin suhteen kakkosvaiheessa - tosin Suomessa pitkälti vielä ykkösvaiheessa.

Kanadassa ollaan siirtymässä hyvää vauhtia kolmosvaiheeseen:

http://www.vitamindcouncil.org/newslett ... -nov.shtml


Voi olla moninaisempi juttu kuten tuossa mietitäänkin. Toisaalta D-vitamiinin toiminta luultavimmin riippuu myös painoindeksistä ja lapsethan ovat äiteineen pullistumassa kuin pullataikinat. Itskein synnyin keisarinleikkauksella ja sain autoimmuunisairauden.

Kalsidiolitestejä pitää todellakin alkaa soveltamaan ja nopeasti kovin kauaahan niitä ei olla osattu tehdäkään. Myös D-vitamiinin kofaktoreista puhuminen on vielä kovin köykäistä, tiedetään että A-vitamiini(t) ja ehkä myös K2-vitamiini toimivat yhteistyössä D-vitamiinin kanssa reseptoritasolla. Se tietenkin on vanhaa tietoa, että D-vitamiini itsessään vaikuttaa haiman gliasolujen geeniekspressioon ja siten näyttelee selkeästi roolia sekä ykkös- että kakkostyypin diabeteksen synnyssä ja kehittymisessä. Ainoa tekijä se ei ilmeisestikään ole. Eikä allasveden klooraustakaan uimahalleissa voine kaikesta syyttää, vaikka allergioita todennäköisesti onkin lisännyt selvästi.

Ykköstyypin diabeteksen korrelointi leveyspiirien kanssa joka tapauksessa on ihan ÄLYTTÖMÄN vahvaa. (San Diego Vitamin D Symposium 2008)

Ystävämme John Cannell toteaa, että 80-luvulta alkanutta trendiä astman, autismin ja ykköstyypin diabeteksen suhteen selittänee parhaiten JUURI silloin alkanut auringonvalon fanaattinen välttely ja kauhistelu. Solutason mekanismeja tunnetaan jo useita.

Tai sitten sitä voisi uuttaa kahvinkeittimellä jauhetusta valkopippurista ja väkevöittää haihduttamalla? Valkopippurissa on enemmän piperiiniä kuin mustassa pippurissa.

http://delano.com/Articles/piperine-multiplies.html

Mutta onko valkopippuri muutoin parempi valinta? Pidän siitä mustaa enemmän, siksi kiinnostaisi tietää. Melkein joka toisessa kuukausi sitten iherbistä tilaamassani ryynissä on bioperiiniä "auttamassa imeytymistä".

Toki vihreä teekin kannattaisi nauttia sitruunamehun kanssa, koska se parantaa EGCG:n imeytymistä massiivisesti estämällä sen hajoamista suoliston alkuosassa. Pikku makukokeilut voivat siis olla myös terveyspommeja. Itse ajattelin kokeilla vihreään luomu-ginsengteeheni tujauttaa jo huomenna sitruunaa.


- -


Hieman teaseria uudesta uutiskirjeestä...

The doses of sunshine or oral vitamin D3 used in healthy children should be designed to maintain 25(OH)D levels above 50 ng/mL. As a rule, in the absence of significant sun exposure, we believe that most healthy children need about 1,000 IU of vitamin D3 daily per 11 kg (25 lb) of body weight to obtain levels greater than 50 ng/mL. Some will need more, and others less. In our opinion, children with chronic illnesses such as autism, diabetes, and/or frequent infections should be supplemented with higher doses of sunshine or vitamin D3, doses adequate to maintain their 25(OH)D levels in the mid-normal of the reference range (65 ng/mL) — and should be so supplemented year-round (p. 868)."

- Cannell JJ, Vieth R, Willett W, Zasloff M, Hathcock JN, White JH, Tanumihardjo SA, Larson-Meyer DE, Bischoff-Ferrari HA, Lamberg-Allardt CJ, Lappe JM, Norman AW, Zittermann A, Whiting SJ, Grant WB, Hollis BW, Giovannucci E. Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic. Ann Otol Rhinol Laryngol. 2008 Nov;117(11):864–70.

Jepjep. Lapsille 17 D-vitamiinitutkijaa suosittelee vähimmäistasoa 125 nmol/l ja siihen pääsemiseen 25 µg per 11 painokiloa.

Toisin sanoen 25-kiloinen tenava tarvitsee minimissään 57 µg joka päivä. Samalla kaavalla itse tarvitsisin vähintään 188 µg päivässä - annos jonka ottaminen tuuditti minut parhaaseen remissioon 15 vuoteen Crohnin taudissa.

Autismista, diabeteksesta ja toistuvista infektioista kärsivien tulisi pitää tasonsa vähintään luokassa 162,5 nmol/l.

Jep, 17 tutkijaa allekirjoittaneina - mukaan lukien suomalainen Christel Lamberg-Allardt. Monella noistakredentiaalit kuuhun asti ja takaisin. Mites nyt suu pannaan?

Tilasin NOW Foodsin 125µg-vahvuista d-vitskua. Kapseli on vielä oliiviöljyssä, ei mainita onko kylmäpuristettua. Ilmaiseina vinkkinä vielä kannattaa tsekata brittien eBay. Halvat postikulut ja EU-alueelta tilattaessa ei tullimaksuja. Tuolta löytyy paljon halpaa kamaa.

Odotukset on kovat, skitsofreniaa vastaan taistellaan, ei vielä diagnosoitu, mutta ehkä tulevaisuudessa. Lisävinkkejä otetaan vastaan

Tuon mukaan valkopippurissa on hieman enemmän piperiiniä kuin mustassa;
3,6% vs. 3,2%
http://www.springerlink.com/content/p26 ... lltext.pdf

Muuten en tiedä, mutta valkopippuria saattaisi saada hienommaksi pulveriksi jauhettuna kuin mustaa pippuria?

Piperiinä voisi ilmeisesti kokeilla myös luomutuotannossa tuholaismyrkkynä:
http://www.jircas.affrc.go.jp/english/p ... 05_13.html

Mikä selittänee pippurin aromiaineen alkuperäisen tarkoituksen..

Vitamin D Councilin uutiskirje, Kesäkuu 2009!

Aiheena raskausaika ja ystävämme Dee.

Niin tuskaisen makeaa settiä aina vauvojen kouristelujen ensihoidon mielettömyydestä Barack Obaman älykkyyden syyhyn (valkoihoinen äiti, syntynyt elokuussa 21 leveyspiirillä)... helmee!!!


Pregnancy and Gestational Vitamin D Deficiency

In the last 3 years, an increasing amount of research suggests that some of the damage done by Vitamin D deficiency is done in-utero, while the fetus is developing. Much of that damage may be permanent, that is, it can not be fully reversed by taking Vitamin D after birth. This research indicates Vitamin D deficiency during pregnancy endangers the mother's life and health, and is the origin for a host of future perils for the child, especially for the child's brain and immune system. Some of the damage done by maternal Vitamin D deficiency may not show up for 30 years. Let's start with the mother.


Incidence of Gestational Vitamin D Deficiency

Dr. Joyce Lee and her colleagues at the University of Michigan studied 40 pregnant women, the majority taking prenatal vitamins. Only two had blood levels of >50 ng/mL and only three had levels >40 ng/mL. That is, 37 of 40 pregnant women had levels below 40 ng/mL, and the majority had levels below 20 ng/mL. More than 25% had levels below 10 ng/mL. Lee JM, Smith JR, Philipp BL, Chen TC, Mathieu J, Holick MF. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr (Phila). 2007 Jan;46(1):42–4.

Dr. Lisa Bodnar, a prolific Vitamin D researcher, and her colleagues at the University of Pittsburg studied 400 pregnant Pennsylvania women; 63% had levels below 30 ng/mL and 44% of the black women in the study had levels below 15 ng/mL. Prenatal vitamins had little effect on the incidence of deficiency. Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr. 2007 Feb;137(2):447–52.

Dr. Dijkstra and colleagues studied 70 pregnant women in the Netherlands, none had levels above 40 ng/mL and 50% had levels below 10 ng/mL. Again, prenatal vitamins appeared to have little effect on 25(OH)D levels, as you might expect since prenatal vitamins only contain 400 IU of Vitamin D. Dijkstra SH, van Beek A, Janssen JW, de Vleeschouwer LH, Huysman WA, van den Akker EL. High prevalence of vitamin D deficiency in newborns of high-risk mothers. Arch Dis Child Fetal Neonatal Ed. 2007 Apr 25.

Thus, more than 95% of pregnant women have 25(OH)D levels below 50 ng/mL, the level that may indicate chronic substrate starvation, that is, they are using up any Vitamin D they have very quickly and do not have enough to store for future use. Pretty scary.


Effects on the Mother
Caesarean section

The rate of Caesarean section in American women has increased from 5% in 1970 to 30% today. Dr. Anne Merewood and her colleagues at Boston University School of Medicine found women with levels below 15 ng/mL were four times more likely to have a Cesarean section than were women with higher levels. Among the few women with levels above 50 ng/mL, the Caesarean section rate was the same as it was in 1970, about 5%. Merewood A, Mehta SD, Chen TC, Bauchner H, Holick MF. Association between vitamin D deficiency and primary cesarean section. J Clin Endocrinol Metab. 2009 Mar;94(3):940–5.


Preeclampsia

Preeclampsia is a common obstetrical condition in which hypertension is combined with excess protein in the urine. It greatly increases the risk of the mother developing eclampsia and then dying from a stroke. Dr. Lisa Bodnar and her colleagues found women with 25(OH)D levels less than 15 ng/mL had a five-fold (5 fold) increase in the risk of preeclampsia. Bodnar LM, Catov JM, Simhan HN, Holick MF, Powers RW, Roberts JM. Maternal vitamin D deficiency increases the risk of preeclampsia. J Clin Endocrinol Metab. 2007 Sep;92(9):3517–22.


Gestational Diabetes

Diabetes during pregnancy affects about 5% of all pregnant women, is increasing in incidence, and may have deleterious effects on the fetus. Dr. Cuilin Zhang and colleagues at the NIH found women with low 25(OH)D levels were almost 3 times more likely to develop diabetes during pregnancy. Zhang C, Qiu C, Hu FB, David RM, van Dam RM, Bralley A, Williams MA. Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus. PLoS ONE. 2008;3(11):e3753.


Bacterial Vaginitis

Dr. Lisa Bodnar and her colleagues found pregnant women with the lowest 25(OH)D level are almost twice as likely to get a bacterial vaginal infection during their pregnancy. Bodnar LM, Krohn MA, Simhan HN. Maternal Vitamin D Deficiency Is Associated with Bacterial Vaginosis in the First Trimester of Pregnancy. J Nutr. 2009 Apr 8.


Effects on the child

Seventeen experts—many of them world-class experts—recently recommended:

"Until we have better information on doses of vitamin D that will reliably provide adequate blood levels of 25(OH)D without toxicity, treatment of vitamin D deficiency in otherwise healthy children should be individualized according to the numerous factors that affect 25(OH)D levels, such as body weight, percent body fat, skin melanin, latitude, season of the year, and sun exposure. The doses of sunshine or oral vitamin D3 used in healthy children should be designed to maintain 25(OH)D levels above 50 ng/mL. As a rule, in the absence of significant sun exposure, we believe that most healthy children need about 1,000 IU of vitamin D3 daily per 11 kg (25 lb) of body weight to obtain levels greater than 50 ng/mL. Some will need more, and others less. In our opinion, children with chronic illnesses such as autism, diabetes, and/or frequent infections should be supplemented with higher doses of sunshine or vitamin D3, doses adequate to maintain their 25(OH)D levels in the mid-normal of the reference range (65 ng/mL) — and should be so supplemented year-round (p. 868)." Cannell JJ, Vieth R, Willett W, Zasloff M, Hathcock JN, White JH, Tanumihardjo SA, Larson-Meyer DE, Bischoff-Ferrari HA, Lamberg-Allardt CJ, Lappe JM, Norman AW, Zittermann A, Whiting SJ, Grant WB, Hollis BW, Giovannucci E. Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic. Ann Otol Rhinol Laryngol. 2008 Nov;117(11):864–70.

That's right. Healthy children need about 1,000 IU per 25 pounds of body weight and their 25(OH)D levels should be >50 ng/mL, year-round.

Eight years before the above recommendations, Professor John McGrath of the Queensland Centre for Mental Health Research theorized that maternal Vitamin D deficiency adversely "imprinted" the fetus, making infants more liable for a host of adult disorders. Research since that time has supported McGrath's theory. Consider, for a minute, what it must be like for John McGrath, to know that maternal Vitamin D deficiency is causing such widespread devastation, to know it could be so easily treated, but to also know he must wait the decades that will be required to deal with the problem. McGrath J. Does 'imprinting' with low prenatal vitamin D contribute to the risk of various adult disorders? Med Hypotheses. 2001 Mar;56(3):367–71.


Schizophrenia

Dr. Dennis Kinney and his colleagues at Harvard published a fascinating paper last month on the role of maternal Vitamin D deficiency in the development of schizophrenia, in support of Dr. McGrath's theory. As they point out, the role of inadequate Vitamin D during brain development appears to "overwhelm" other effects, explaining why schizophrenia has so many of the footprints of a maternal Vitamin D deficiency disorder, such as strong latitudinal variation, excess winter births, and skin color. Kinney DK, Teixeira P, Hsu D, Napoleon SC, Crowley DJ, Miller A, Hyman W, Huang E. Relation of schizophrenia prevalence to latitude, climate, fish consumption, infant mortality, and skin color: a role for prenatal vitamin d deficiency and infections? Schizophr Bull. 2009 May;35(3):582–95.
Autism

I will say not more, other than to point out that Scientific American ran a lengthy article last month on my autism theory but the editors insisted that the author not cite me, nor my paper, because I am "not a scientist." Gabrielle Glaser. What If Vitamin D Deficiency Is a Cause of Autism? 2009 April 24. Scientific American.


Mental Retardation

The only evidence that Vitamin D deficiency is a common cause of mental retardation is from researchers at the CDC who found mild mental retardation is twice as common among African Americans as whites, and that the politically correct explanation—socioeconomic factors—cannot explain it. If latitudinal studies of mild mental retardation exist, I am unable to locate them. Yeargin-Allsopp M, Drews CD, Decoufle P, Murphy CC. Mild mental retardation in black and white children in metropolitan Atlanta: a case-control study. Am J Public Health 1995;85(3):324–8. Drews CD, Yeargin-Allsopp M, Decoufle P, Murphy CC. Variation in the influence of selected sociodemographic risk factors for mental retardation. Am J Public Health 1995;85(3):329–34.

Of course, it is claimed you are a racist if you believe these studies. In fact, a number of writers have told me their editors will not allow writers to discuss these studies in their stories. I am glad these studies were conducted by researchers at the CDC. Although, I worry about their political longevity at the CDC after reporting such findings.

I will mention one other fact (at my peril) and that is the fact that a very smart man, President Barack Obama, was born in the late summer (August) and has a brain that developed in a womb covered in white skin, during the spring and summer, in the subtropics (Latitude 21 degrees North), during an age before sun-avoidance was the mantra (1961). Make what you want to of that fact. My point is that whites living at temperate latitudes may have a huge developmental advantage over blacks, an advantage that begins immediately after conception, an advantage that has nothing to do with innate genetic ability and everything to do with environment. ( -Nn )


Newborn Lower Respiratory Tract Infection

Newborn babies are vulnerable to infections in their lungs and women with the lowest 25(OH)D level during pregnancy were much more likely to have their newborn in the ICU being treated for lower respiratory tract infections. Drs. Walker and Modlin at UCLA recently presented reasons why viral pneumonia is probably only one of many pediatric Vitamin D deficient infections. Karatekin G, Kaya A, Salihoğlu O, Balci H, Nuhoğlu A. Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers. Eur J Clin Nutr. 2009 Apr;63(4):473–7. Walker VP, Modlin RL. The Vitamin D Connection to Pediatric Infections and Immune Function. Pediatr Res. 2009 Jan 28.


Birth weight

While conflicting results exist on the effects of maternal Vitamin D deficiency and birth weight, the majority of the studies find an effect. Furthermore, the studies are comparing women who have virtually no intake to women who have minuscule intakes. For example, women who ingested around 600 IU per day were more likely to have normal weight babies compared to women whose intake was less than 300 IU per day. One can only wonder what would happen if pregnant women had adequate intakes? Drs. Scholl and Chen, at the Department of Obstetrics at the University of Medicine and Dentistry of New Jersey, concluded pregnant women need 6,000 IU per day, not the 400 IU/day contained in prenatal vitamins. Scholl TO, Chen X. Vitamin D intake during pregnancy: association with maternal characteristics and infant birth weight. Early Hum Dev. 2009 Apr;85(4):231–4.


Diabetes

My old nemesis, cod liver oil, when given during pregnancy resulted in children who were three times less likely to develop juvenile diabetes before the age of 15. Of course, this was back when cod liver oil had meaningful amounts of Vitamin D (these Norwegian mothers were taking cod liver oil in the 1980s). Stene LC, Ulriksen J, Magnus P, Joner G. Use of cod liver oil during pregnancy associated with lower risk of Type I diabetes in the offspring. Diabetologia. 2000 Sep;43(9):1093–8.


Seizures

Newborns frequently have seizures and those seizures are almost always due to low blood calcium. This problem is so common that many newborns are given a prophylactic injection of calcium. In 1978, researchers found such hypocalcemia can easily be prevented by giving Vitamin D. Sadly, standard treatment remains—not Vitamin D, but calcium and an analogue of activated Vitamin D. Such analogues do not correct Vitamin D deficiency. The fact that this was known in 1978 and has been routinely ignored by obstetricians since then should give you pause. Do not think science will solve the Vitamin D problem. Science simply points the way, activists must change the practice. Fleischman AR, Rosen JF, Nathenson G. 25-Hydroxycholecalciferol for early neonatal hypocalcemia. Occurrence in premature newborns. Am J Dis Child. 1978 Oct;132(10):973–7.


Heart Failure

Idiopathic infant heart failure is often fatal. Of course, idiopathic to whom? The uninformed cardiologists who do not recognize severe infantile Vitamin D deficiency? Luckily, for 16 infants, Dr. Maiya, Dr. Burch, and colleagues at the Great Ormand Street Hospital for Children are not among them. Maiya S, Sullivan I, Allgrove J, Yates R, Malone M, Brain C, Archer N, Mok Q, Daubeney P, Tulloh R, Burch M. Hypocalcaemia and vitamin D deficiency: an important, but preventable, cause of life-threatening infant heart failure. Heart. 2008 May;94(5):581–4.


Weak bones

Dr. Muhammad Javaid and colleagues at the University of Southampton found that children of Vitamin D deficient mothers were much more likely to have weak bones 9 years later. Dr. Adrian Sayers and Jonathan Tobias of the University of Bristol recently found the same thing when they looked at maternal sun-exposure. Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher BJ, Arden NK, Godfrey KM, Cooper C; Princess Anne Hospital Study Group. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet. 2006 Jan 7;367(9504):36–43. Sayers A, Tobias JH. Estimated maternal ultraviolet B exposure levels in pregnancy influence skeletal development of the child. J Clin Endocrinol Metab. 2009 Mar;94(3):765–71.


Brain Tumors

John McGrath's group discovered that children with astrocytomas and ependymomas (brain tumors you do not want your child to have) were more likely to be born in the winter. Ko P, Eyles D, Burne T, Mackay-Sim A, McGrath JJ. Season of birth and risk of brain tumors in adults. Neurology. 2005 Apr 12;64(7):1317.


Epilepsy

Three studies have found that epileptic patients are much more likely to be born in the winter. Dr. Marco Procopio of the Priory Hospital Hove in Sussex has written all three. Procopio M, Marriott PK, Davies RJ. Seasonality of birth in epilepsy: a Southern Hemisphere study. Seizure. 2006 Jan;15(1):17–21.


Craniotabes

Craniotabes is softening of the skull bones that occurs in 1/3 of "normal" newborns. Recent evidence indicates it is yet another sign and sequela of maternal vitamin D deficiency. Yorifuji J, Yorifuji T, Tachibana K, Nagai S, Kawai M, Momoi T, Nagasaka H, Hatayama H, Nakahata T. Craniotabes in normal newborns: the earliest sign of subclinical vitamin D deficiency. J Clin Endocrinol Metab. 2008 May;93(5):1784–8.


Cavities

Dr. Robert Schroth from the University of Manitoba reported that mothers of children who developed cavities at an early age had significantly lower vitamin D levels during pregnancy than those whose children were cavity-free. Megan Rauscher. Prenatal vitamin D linked to kids' dental health. 2009. Reuters.


Asthma

The extant data here is conflicting. Two studies have found higher Vitamin D intakes during pregnancy decrease the risk of asthma in later childhood and one has found the opposite. The best review of the issue is by Drs. Augusto Litonjua and Scott Weiss, at Harvard, who conclude that the current epidemic of asthma among our children is related to both gestational and ongoing childhood vitamin D deficiency. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol. 2007 Nov;120(5):1031–5.

Furthermore, a very recent study by Dr. John Brehm and the same Harvard group found low Vitamin D levels in asthmatic children were associated with hospitalization, medication use, and disease severity. Brehm JM, Celedón JC, Soto-Quiros ME, Avila L, Hunninghake GM, Forno E, Laskey D, Sylvia JS, Hollis BW, Weiss ST, Litonjua AA. Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med. 2009 May 1;179(9):765–71.

In case you are wondering, black children are four times more likely than white children to be hospitalized or die from asthma. Akinbami LJ, Schoendorf KC. Trends in childhood asthma: prevalence, health care utilization, and mortality. Pediatrics. 2002 Aug;110(2 Pt 1):315–22.

My experience, both at the hospital and via my readers, is that asthma improves—albeit sometimes slowly—when adequate doses of Vitamin D are taken. However, Vitamin D does not appear to be a cure, like it is in some other conditions. I suspect children with asthma have suffered both gestational and ongoing childhood Vitamin D deficiency that probably altered, perhaps permanently, their immune system.


The Vitamin D Council's Effort

We recently ran a ¼ page announcement in OB/GYN News and the American Journal of Obstetrics and Gynecology (AJOG). Unfortunately, the editor of AJOG censored our announcement after its first month, but we were able to get the full, three-month run in OB/GYN News. We also sent a very similar email to 18,000 obstetricians in the United States. The total cost to the Vitamin D Council for this campaign was about $12,000.00.

The announcement simply pointed out that the American Academy of Pediatrics (AAP) recently recommended that all pregnant women have a 25(OH)D blood test because Vitamin D is important for normal fetal development (p. 1145):

"Given the growing evidence that adequate maternal vitamin D status is essential during pregnancy, not only for maternal well-being but also for fetal development, health care professionals who provide obstetric care should consider assessing maternal vitamin D status by measuring the 25-OH-D concentrations of pregnant women. On an individual basis, a mother should be supplemented with adequate amounts of vitamin D3 to ensure that her 25-OH-D levels are in a sufficient range (>32 ng/mL). The knowledge that prenatal vitamins containing 400 IU of vitamin D3 have little effect on circulating maternal 25-OH-D concentrations, especially during the winter months, should be imparted to all health care professionals." Wagner CL, Greer FR; American Academy of Pediatrics Section on breastfeeding; American Academy of Pediatrics Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics. 2008 Nov;122(5):1142–52.

As the AAP recommendation came from an official medical body, to medical malpractice attorneys it represents evidence of a "standard of care" for future lawsuits. We also reminded obstetricians that the statute of limitations on malpractice suits does not toll (begin) until the injured party recognizes the injury. That is, the parents of a 5-year-old child diagnosed with autism five years in the future may bring suit against that obstetrician for how the child was treated during his time in the uterus, citing the 2008 AAP's recommendation as a standard of care. Obstetricians are already burdened with lawsuits, but they could decrease the number of suits significantly if they would just take the time to learn about Vitamin D.

Finally, we used our last $12,000 to produce and run a television announcement in the Washington, D.C. TV market, entitled Pregnancy and Vitamin D.


What can you do?

Most people want to do good—at least some good—in their lives. The endless pursuit of the God-almighty dollar, better clothes, better houses and better vacations than your neighbors eventually leaves a hole in your soul. Here is an opportunity to fill it.

If you don't feel that soul hole, try a meditation I learned at Esalen Institute in the 1980s and have practiced ever since. Lie on the floor and pretend you are dead in your grave. Feel the worms, smell the rot, sense the finality. Then, when you really feel dead, visualize your gravestone above. What does it say? "Here lies Robert; he had a big fancy house." "Here lies Vanessa; she wore beautiful clothes and had four face lifts." Here lies Michael; he made a billion dollars." Through this meditation, I realized I want my gravestone to say, "Here lies John, he did something good."

One good thing you can do is simply tell every pregnant woman and women thinking of getting pregnant that she needs to take more Vitamin D, a lot more. Pregnant women need a minimum of 5,000 IU per day and even that dose will not achieve 25(OH)D levels of >50 ng/mL in all women. Why not buy a few bottles of 5,000 IU capsules and hand out the bottles to your pregnant friends? You can get 250 vitamin D capsules for 15 bucks. Or, forward this email to them. Show them our Pregnancy and Vitamin D public service announcement.

If you want to do more, why not get a copy of our Pregnancy and Vitamin D public service announcement by emailing our webmaster at webmaster@vitamindcouncil.org (the ad is not copyrighted) and then pay to run it on a TV station in your hometown? You can easily add a caption at the bottom saying this public service announcement is being sponsored by your company, combining a good deed with good business.

Alas, no glory will be yours, at least in this life. No woman will ever thank you for the schizophrenic child she never had, for the trips to the emergency room with a breathless child that she never made, for the repetitive moaning of the autistic child she never endured. Although, she may wonder why her pregnancy was so easy and why her infant is so healthy, alert, active, and smart.

Mielialasi saattaa kohota:
Piperiini lisää serotoniinisynteesiä.

http://www.ncbi.nlm.nih.gov/pubmed/6210090

Muuten,musta ja valkopippurit ovat saman pensaan marjoja. Valkopippuri on kuorittu versio mustapippurista. Viherpippuri taas on raaka versio.