Leusiini ja muut BCAA-aminohapot
[size=150:2up9ml54]Leucine supplements could promote weight loss [/size:2up9ml54]
A low-dose leucine supplement to a normal diet could increase body fat loss, say Brazilian researchers who have reported positive results on rats.
The new study, published in the journal Nutrition (Vol. 22, pp. 520-527), used 28 Wistar rats eating the model AIN-93M diet for three weeks. The rats were subsequently divided into two groups, one continued to eat the normal diet, while the second group ate the diet plus a 0.6 per cent L-leucine supplement for a further six weeks.
"Significant decreases in the amount (minus 24.5 per cent) and percentage (minus 22.6 per cent) of body fat were observed for the leucine group compared with the control group," reported lead author Jose Donato, Jr. from the University of Sai Paulo.
"The fact that even moderate doses of leucine have shown positive results is extremely relevant for the clinical application and extrapolation of these data to humans," concluded the researchers. 1
Abstract Branched chain amino acids (BCAA), particularly leucine, have been suggested to be ergogenic for both endurance and strength/power performance. This study investigated the effects of dietary leucine supplementation on the exercise performance of outrigger canoeists. Thirteen (ten female, three male) competitive outrigger canoeists [aged 31.6 (2.2) year, VO2max 47.1 (2.0) ml kg−1 min−1] underwent testing before and after 6-week supplementation with either capsulated L-leucine (45 mg kg−1 d−1; n=6) or placebo (cornflour; n=7). Testing included anthropometry, 10 s upper body power and work and a row to exhaustion at 70–75% maximal aerobic power where perceived exertion (RPE), heart rate (HR) and plasma BCAA and tryptophan concentrations were assessed. Leucine supplementation resulted in significant increases in plasma leucine and total BCAA concentrations. Upper body power and work significantly increased in both groups after supplementation but power was significantly greater after leucine supplementation compared to the placebo [6.7 (0.7) v. 6.0 (0.7) W kg−1]. Rowing time significantly increased [77.6 (6.3)–88.3 (7.3) min] and average RPE significantly decreased [14.5 (1.5)–12.9 (1.4)] with leucine supplementation while these variables were unchanged with the placebo. Leucine supplementation had no effect on the plasma tryptophan to BCAA ratio, HR or anthropometric variables. Six weeks’ dietary leucine supplementation significantly improved endurance performance and upper body power in outrigger canoeists without significant change in the plasma ratio of tryptophan to BCAA. 2
Aika kick-ass -kamaa tuo leusiini. Otin asian esille, koska olen käyttänyt l-leusiinia muutaman viikon ja hyvin potkii. Kommentteja?
Pretending to be certain about propositions for which no evidence is even conceivable—is both an intellectual and a moral failing. —Sam Harris