[size=85:1qzoz6t4]American Journal of Clinical Nutrition in January 2009 ( Am J Clin Nutr. 2009 January ; 89(1): 283–289)[/size:1qzoz6t4]
[size=150:1qzoz6t4]Dietary carbohydrates, fiber, and breast cancer risk in Chinese women[/size:1qzoz6t4]
Background—Few studies have investigated the association of dietary carbohydrate and fiber intake with breast cancer risk in Chinese women, where carbohydrate intake is traditionally high.
Objective—To prospectively evaluate the association of dietary carbohydrates, glycemic index,
Design—A total of 74,942 women aged 40–70 years were recruited into the Shanghai Women’s Health Study, a population-based cohort study. Dietary intake was assessed by in-person interviews.
Cox proportional hazards regression model was used to evaluate associations.
Results—During an average of 7.35 years of follow-up, 616 incident breast cancer cases were documented. Higher carbohydrate intake was associated with a higher risk of premenopausal breast cancer (p for trend=0.002).
As compared with the lowest quintile, the hazard ratios and 95% confidence intervals (in parenthesis) were 1.47 (1.00,2.32) and 2.01 (1.26,3.19) for the fourth and fifth quintile, respectively. A similar pattern was found for glycemic load.
The association between carbohydrate intake and breast cancer was significantly modified by age; the increased breast cancer risk associated with carbohydrate intake was restricted to women who were younger than 50 years.
No significant association of breast cancer risk with glycemic index or dietary fiber intake was found.
Conclusion—Our data suggest that high carbohydrate intake and a diet with high glycemic load may be associated with breast cancer risk in premenopausal women or women younger than 50 years.[/list:u:1qzoz6t4]
Ohoh - hiilarien suurempi saanti näkyy rintasyöpäriskin lisääntymisenä. Glykeemisellä indeksillä ei ollu merkitystä, riskin nousu koski tosin vain alle 50-vuotiaita naisia.
Nyt pitäisi tutkia, mitä tapahtuu kun toiseksi muuttujaksi otetaan jodin saanti - lienee Japani paras paikka tällaisen tutkimiseen.
Samassa lehdessä oli myös tällainen:
[size=150:1qzoz6t4]Fruit and vegetable intake and risk of cancer: a prospective cohort study[/size:1qzoz6t4] (Am J Clin Nutr. 2009 January; 89(1): 347–353)
We performed a prospective study among the cohort of the National Institutes of Health–AARP Diet and Health Study.
From 1995 to 2003, we identified 15,792 and 35,071 cancer cases in 195,229 women and 288,109 men, respectively.
In this large US prospective cohort study, we observed no association between fruit and vegetable intake and total cancer incidence.
A pooled analysis of the Health Professionals Follow-Up Study and the Nurses’ Health Study as well as the Japanese Public Health Center Based Prospective Study found no evidence of an association between fruit and vegetable intake and total cancer incidence.[/list:u:1qzoz6t4]
Vihannesten ja hedelmien syönti ei suojaakaan syöviltä - ollenkaan ?
Tervetuloa vuoteen 2010.
Pretending to be certain about propositions for which no evidence is even conceivable—is both an intellectual and a moral failing. —Sam Harris