Seuraa 
Viestejä1
Liittynyt17.4.2017

Eli onko ainoastaa NAD+ (nikotiiniamidiadeniinidinukleotidi) hyödyllinen ?

Kommentit (8)

jussipussi
Seuraa 
Viestejä40495
Liittynyt6.12.2009

Käyttäjä4080 kirjoitti:
Eli onko ainoastaa NAD+ (nikotiiniamidiadeniinidinukleotidi) hyödyllinen ?

Katsotaan sanoi maallikko.

"Landmark Vitamin Discovery Could Prevent Miscarriages And Birth Defects

"The most important discovery for pregnant women since folate."

A simple vitamin supplement could have the potential to prevent miscarriages and birth defects, according to a 12-year study by scientists in Australia.

Researchers have identified a deficiency in a developmental molecule called NAD that can keep a baby's organs from forming properly in the womb – but the shortfall could be addressed by pregnant women taking vitamin B3, which may prevent a range of birth defects.

It's the first time that NAD (aka nicotinamide adenine dinucleotide) has been linked to congenital abnormalities, identifying a previously unknown cause of birth defects – along with the supplement that might treat the problem.

"The ramifications are likely to be huge," says developmental geneticist Sally Dunwoodie from the Victor Chang Institute.

"This has the potential to significantly reduce the number of miscarriages and birth defects around the world, and I do not use those words lightly."

http://www.sciencealert.com/landmark-vitamin-discovery-could-prevent-mis...

Odotellaan uutista kotimaisella.

Neonomide
Seuraa 
Viestejä14191
Liittynyt23.6.2005

Testaan pian Nicotinamide Ribosidea, kunhan tulee treenikaudella plateau vastaan.

Pretending to be certain about propositions for which no evidence is even conceivable—is both an intellectual and a moral failing. —Sam Harris

jussipussi
Seuraa 
Viestejä40495
Liittynyt6.12.2009

Neonomide kirjoitti:
Testaan pian Nicotinamide Ribosidea, kunhan tulee treenikaudella plateau vastaan.
B3.n kauttahan sitä saa myös. Punastuttaa ja kihelmöi hetkin toki.

jussipussi
Seuraa 
Viestejä40495
Liittynyt6.12.2009

jussipussi kirjoitti:
Aiheeseen liittyen.

"A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention"

http://www.nejm.org/doi/full/10.1056/NEJMoa1506197#t=article .

https://www.cancercouncil.com.au/blog/the-role-of-vitamin-b3-in-reducing...

"Vitamin B3, Nicotinamide, Shown as Inexpensive Chemopreventive for Non-Melanoma Skin Cancer

A new opportunity for skin cancer prevention may be as near and as simple as taking a vitamin available over-the-counter, according to a large Australian randomized Phase III placebo-controlled trial reported at the American Society of Clinical Oncology Annual Meeting (Abstract 9000).

Oral nicotinamide (vitamin B3) reduced the number of non-melanoma skin cancers and actinic keratoses by 23 percent over a year in high-risk patients with a history of basal cell or squamous cell carcinoma, according to researchers at the University of Sydney.

The data were presented in an ASCO teleconference for reporters in advance of the Annual Meeting.

Diona Damian, MBBS, PhD, Professor of Dermatology at the University of Sydney Medical School, senior author on the study, noted that skin cancer is the most common cancer in fair-skinned populations worldwide, and that the incidence in Australia is four times that of all other cancers combined.

Nicotinamide—which Damian emphasized is not the same as nicotinic acid, a different form of vitamin B3—is safe and affordable, and available over the counter in most countries."

http://journals.lww.com/oncology-times/Fulltext/2015/06250/Vitamin_B3,_N... .

Neonomide
Seuraa 
Viestejä14191
Liittynyt23.6.2005

jussipussi kirjoitti:
Neonomide kirjoitti:
Testaan pian Nicotinamide Ribosidea, kunhan tulee treenikaudella plateau vastaan.
B3.n kauttahan sitä saa myös. Punastuttaa ja kihelmöi hetkin toki.

Näyttäisi, että NR on alustavasti parempi kuin niasiini/nikotiiniamidi nostamaan sirtuiinitasoja ja NAD-metaboliitteja, mutta N=1 on tosiaan hyvin alustavaa dataa.

""

In particular, the researchers compared the ability of all three NAD+ precursor vitamins -- NR, niacin, and nicotinamide -- to boost NAD+ metabolism and stimulate the activity of certain enzymes, which have been linked to longevity and health benefits. The study showed for the first time that oral NR is superior to nicotinamide, which is better than niacin in terms of the total amount of NAD+ produced at an equivalent dose. NR was also the best of the three in stimulating the activity of sirtuin enzymes. However, in this case, NR was the best at stimulating sirtuin-like activities, followed by niacin, followed by nicotinamide.

""

https://www.sciencedaily.com/releases/2016/10/161010135418.htm

Alunperin kiinnoistuin NAD-buustauksesta ja NR:stä kun luin tämän tweetstormin lähdeviitteineen:

https://twitter.com/JohnDPMorgan/status/853482712299995136

Kokeilen ensin Life Extensionin versiolla, ja jos jotain jännää tapahtuu, niin vaihdan merkkiä halvempaan ja raportoin vaikka tänne.

Pretending to be certain about propositions for which no evidence is even conceivable—is both an intellectual and a moral failing. —Sam Harris

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